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OCT4 accelerates tumorigenesis through activating JAK/STAT signaling in ovarian cancer side population cells

BACKGROUND: Although surgery, chemotherapy, and radiotherapy eliminate clinically apparent ovarian tumor, the 5-year survival rate is no more than 45%. Cancer stem cells (CSCs) have been identified for precaution of tumor metastasis and recurrence in many kinds of cancers including ovarian cancer. A...

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Detalles Bibliográficos
Autores principales: Ruan, Zhengyi, Yang, Xingyu, Cheng, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314052/
https://www.ncbi.nlm.nih.gov/pubmed/30643464
http://dx.doi.org/10.2147/CMAR.S180418