A New in Vitro Model of GDLD by Knocking Out TACSTD2 and Its Paralogous Gene EpCAM in Human Corneal Epithelial Cells

PURPOSE: Gelatinous drop-like corneal dystrophy (GDLD) is a rare autosomal recessive corneal dystrophy that causes severe vision loss. Because of its poor prognosis, there is a demand for novel treatments for GDLD. Here, we establish a new in vitro disease model of GDLD based on immortalized human c...

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Detalles Bibliográficos
Autores principales: Xu, Peng, Kai, Chifune, Kawasaki, Satoshi, Kobayashi, Yuki, Yamamoto, Kouji, Tsujikawa, Motokazu, Hayashi, Ryuhei, Nishida, Kohji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314060/
https://www.ncbi.nlm.nih.gov/pubmed/30619650
http://dx.doi.org/10.1167/tvst.7.6.30

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