Integration of DNA methylation patterns and genetic variation in human pediatric tissues help inform EWAS design and interpretation

BACKGROUND: The widespread use of accessible peripheral tissues for epigenetic analyses has prompted increasing interest in the study of tissue-specific DNA methylation (DNAm) variation in human populations. To date, characterizations of inter-individual DNAm variability and DNAm concordance across...

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Detalles Bibliográficos
Autores principales: Islam, Sumaiya A., Goodman, Sarah J., MacIsaac, Julia L., Obradović, Jelena, Barr, Ronald G., Boyce, W. Thomas, Kobor, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314079/
https://www.ncbi.nlm.nih.gov/pubmed/30602389
http://dx.doi.org/10.1186/s13072-018-0245-6

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