Partial Rescue of Ocular Pigment Cells and Structure by Inducible Ectopic Expression of Mitf-M in MITF-Deficient Mice

PURPOSE: Complete deficiency of microphthalmia transcription factor (MITF) in Mitf(mi-vga9/mi-vga9) mice is associated with microphthalmia, retinal dysplasia, and albinism. We investigated the ability of dopachrome tautomerase (DCT) promoter-mediated inducible ectopic expression of Mitf-M to rescue...

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Detalles Bibliográficos
Autores principales: Michael, Helen T., Graff-Cherry, Cari, Chin, Sung, Rauck, Corinne, Habtemichael, Amelework D., Bunda, Patricia, Smith, Tunde, Campos, Maria M., Bharti, Kapil, Arnheiter, Heinz, Merlino, Glenn, Day, Chi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314104/
https://www.ncbi.nlm.nih.gov/pubmed/30590377
http://dx.doi.org/10.1167/iovs.18-25186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314104/
https://www.ncbi.nlm.nih.gov/pubmed/30590377
http://dx.doi.org/10.1167/iovs.18-25186

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