Cargando…
Human papillomavirus and the landscape of secondary genetic alterations in oral cancers
Human papillomavirus (HPV) is a necessary but insufficient cause of a subset of oral squamous cell carcinomas (OSCCs) that is increasing markedly in frequency. To identify contributory, secondary genetic alterations in these cancers, we used comprehensive genomics methods to compare 149 HPV-positive...
Autores principales: | Gillison, Maura L., Akagi, Keiko, Xiao, Weihong, Jiang, Bo, Pickard, Robert K.L., Li, Jingfeng, Swanson, Benjamin J., Agrawal, Amit D., Zucker, Mark, Stache-Crain, Birgit, Emde, Anne-Katrin, Geiger, Heather M., Robine, Nicolas, Coombes, Kevin R., Symer, David E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314162/ https://www.ncbi.nlm.nih.gov/pubmed/30563911 http://dx.doi.org/10.1101/gr.241141.118 |
Ejemplares similares
-
Diverse tumorigenic consequences of human papillomavirus integration in primary oropharyngeal cancers
por: Symer, David E., et al.
Publicado: (2022) -
Intratumoral Heterogeneity and Clonal Evolution Induced by HPV Integration
por: Akagi, Keiko, et al.
Publicado: (2023) -
Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability
por: Akagi, Keiko, et al.
Publicado: (2014) -
HPV integration hijacks and multimerizes a cellular enhancer to generate a viral-cellular super-enhancer that drives high viral oncogene expression
por: Warburton, Alix, et al.
Publicado: (2018) -
An antisense promoter in mouse L1 retrotransposon open reading frame-1 initiates expression of diverse fusion transcripts and limits retrotransposition
por: Li, Jingfeng, et al.
Publicado: (2014)