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Widespread roles of enhancer-like transposable elements in cell identity and long-range genomic interactions

A few families of transposable elements (TEs) have been shown to evolve into cis-regulatory elements (CREs). Here, to extend these studies to all classes of TEs in the human genome, we identified widespread enhancer-like repeats (ELRs) and find that ELRs reliably mark cell identities, are enriched f...

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Detalles Bibliográficos
Autores principales: Cao, Yaqiang, Chen, Guoyu, Wu, Gang, Zhang, Xiaoli, McDermott, Joseph, Chen, Xingwei, Xu, Chi, Jiang, Quanlong, Chen, Zhaoxiong, Zeng, Yingying, Ai, Daosheng, Huang, Yi, Han, Jing-Dong J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314169/
https://www.ncbi.nlm.nih.gov/pubmed/30455182
http://dx.doi.org/10.1101/gr.235747.118