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Hepatic VLDL secretion: DGAT1 determines particle size but not particle number, which can be supported entirely by DGAT2

We investigated whether, in view of its activity being expressed on both aspects of the endoplasmic reticulum (ER; dual membrane topology), diacylglycerol acyltransferase 1 (DGAT1) plays a distinctive role in determining the triglyceride (TAG) content of VLDL particles secreted by the liver. Mice in...

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Detalles Bibliográficos
Autores principales:	Irshad, Zehra, Chmel, Nikola, Adya, Raghu, Zammit, Victor A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Biochemistry and Molecular Biology 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314258/ https://www.ncbi.nlm.nih.gov/pubmed/30397187 http://dx.doi.org/10.1194/jlr.M089300

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