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Co-delivery doxorubicin and silybin for anti-hepatoma via enhanced oral hepatic-targeted efficiency
BACKGROUND: To establish the combination of doxorubicin (DOX) and silybin (SLB) in oral hepatic-targeting liposomes with the goal of reducing cardiotoxic side effects and improve oral hepatoma treatment. METHODS: Distearoylphosphatidylethanolamine–polyethylene glycol–cholic acid-modified liposomes (...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314320/ https://www.ncbi.nlm.nih.gov/pubmed/30643408 http://dx.doi.org/10.2147/IJN.S187888 |