Inotropic interventions do not change the resting state of myosin motors during cardiac diastole

When striated (skeletal and cardiac) muscle is in its relaxed state, myosin motors are packed in helical tracks on the surface of the thick filament, folded toward the center of the sarcomere, and unable to bind actin or hydrolyze ATP (OFF state). This raises the question of whatthe mechanism is tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Caremani, Marco, Pinzauti, Francesca, Powers, Joseph D., Governali, Serena, Narayanan, Theyencheri, Stienen, Ger J.M., Reconditi, Massimo, Linari, Marco, Lombardi, Vincenzo, Piazzesi, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314382/
https://www.ncbi.nlm.nih.gov/pubmed/30510036
http://dx.doi.org/10.1085/jgp.201812196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314382/
https://www.ncbi.nlm.nih.gov/pubmed/30510036
http://dx.doi.org/10.1085/jgp.201812196

Ejemplares similares