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Recovery of left ventricular function following in vivo reexpression of cardiac myosin binding protein C

The loss of cardiac myosin binding protein C (cMyBP-C) results in left ventricular dilation, cardiac hypertrophy, and impaired ventricular function in both constitutive and conditional cMyBP-C knockout (MYBPC3 null) mice. It remains unclear whether the structural and functional phenotypes expressed...

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Detalles Bibliográficos
Autores principales: Giles, Jasmine, Patel, Jitandrakumar R., Miller, Adam, Iverson, Elizabeth, Fitzsimons, Daniel, Moss, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314388/
https://www.ncbi.nlm.nih.gov/pubmed/30573635
http://dx.doi.org/10.1085/jgp.201812238