Cargando…
Neutrophils facilitate ovarian cancer premetastatic niche formation in the omentum
Ovarian cancer preferentially metastasizes to the omentum, a fatty tissue characterized by immune structures called milky spots, but the cellular dynamics that direct this tropism are unknown. Here, we identified that neutrophil influx into the omentum is a prerequisite premetastatic step in orthoto...
Autores principales: | Lee, WonJae, Ko, Song Yi, Mohamed, Muhaned S., Kenny, Hilary A., Lengyel, Ernst, Naora, Honami |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314534/ https://www.ncbi.nlm.nih.gov/pubmed/30567719 http://dx.doi.org/10.1084/jem.20181170 |
Ejemplares similares
-
Normal saline remodels the omentum and stimulates its receptivity for transcoelomic metastasis
por: Akasaka, Hironari, et al.
Publicado: (2023) -
The omentum, a niche for premetastatic ovarian cancer
por: Ma, Xiaojing
Publicado: (2020) -
Neutrophils fertilize the pre-metastatic niche
por: Lee, WonJae, et al.
Publicado: (2019) -
The Heterogeneity of Neutrophil Recruitment in the Tumor Microenvironment and the Formation of Premetastatic Niches
por: Xing, Xin, et al.
Publicado: (2021) -
Cancer-derived small extracellular vesicles promote angiogenesis by heparin-bound, bevacizumab-insensitive VEGF, independent of vesicle uptake
por: Ko, Song Yi, et al.
Publicado: (2019)