Processive flow by biased polymerization mediates the slow axonal transport of actin

Classic pulse-chase studies have shown that actin is conveyed in slow axonal transport, but the mechanistic basis for this movement is unknown. Recently, we reported that axonal actin was surprisingly dynamic, with focal assembly/disassembly events (“actin hotspots”) and elongating polymers along th...

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Detalles Bibliográficos
Autores principales: Chakrabarty, Nilaj, Dubey, Pankaj, Tang, Yong, Ganguly, Archan, Ladt, Kelsey, Leterrier, Christophe, Jung, Peter, Roy, Subhojit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314539/
https://www.ncbi.nlm.nih.gov/pubmed/30401699
http://dx.doi.org/10.1083/jcb.201711022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314539/
https://www.ncbi.nlm.nih.gov/pubmed/30401699
http://dx.doi.org/10.1083/jcb.201711022

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