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Automated profiling of growth cone heterogeneity defines relations between morphology and motility

Growth cones are complex, motile structures at the tip of an outgrowing neurite. They often exhibit a high density of filopodia (thin actin bundles), which complicates the unbiased quantification of their morphologies by software. Contemporary image processing methods require extensive tuning of seg...

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Detalles Bibliográficos
Autores principales: Bagonis, Maria M., Fusco, Ludovico, Pertz, Olivier, Danuser, Gaudenz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314545/
https://www.ncbi.nlm.nih.gov/pubmed/30523041
http://dx.doi.org/10.1083/jcb.201711023