ATP13A2 facilitates HDAC6 recruitment to lysosome to promote autophagosome–lysosome fusion

Mutations in ATP13A2 cause Kufor-Rakeb syndrome, an autosomal recessive form of juvenile-onset atypical Parkinson’s disease (PD). Recent work tied ATP13A2 to autophagy and other cellular features of neurodegeneration, but how ATP13A2 governs numerous cellular functions in PD pathogenesis is not unde...

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Detalles Bibliográficos
Autores principales: Wang, Ruoxi, Tan, Jieqiong, Chen, Tingting, Han, Hailong, Tian, Runyi, Tan, Ya, Wu, Yiming, Cui, Jingyi, Chen, Fang, Li, Jie, Lv, Lu, Guan, Xinjie, Shang, Shuai, Lu, Jiahong, Zhang, Zhuohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314552/
https://www.ncbi.nlm.nih.gov/pubmed/30538141
http://dx.doi.org/10.1083/jcb.201804165

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