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The interdependence of gene-regulatory elements and the 3D genome

Imaging studies, high-resolution chromatin conformation maps, and genome-wide occupancy data of architectural proteins have revealed that genome topology is tightly intertwined with gene expression. Cross-talk between gene-regulatory elements is often organized within insulated neighborhoods, and re...

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Detalles Bibliográficos
Autores principales: Vermunt, Marit W., Zhang, Di, Blobel, Gerd A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314554/
https://www.ncbi.nlm.nih.gov/pubmed/30442643
http://dx.doi.org/10.1083/jcb.201809040