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Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins

Collectins such as mannose-binding lectin (MBL) and surfactant protein D (SP-D) become temporarily deposited in extravascular compartments after tissue injury and perform immune-stimulatory or inflammation-limiting functions. However, their turnover mechanisms, necessary to prevent excessive tissue...

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Detalles Bibliográficos
Autores principales: Jürgensen, Henrik J., Nørregaard, Kirstine S., Sibree, Megan M., Santoni-Rugiu, Eric, Madsen, Daniel H., Wassilew, Katharina, Krustrup, Dorrit, Garred, Peter, Bugge, Thomas H., Engelholm, Lars H., Behrendt, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314555/
https://www.ncbi.nlm.nih.gov/pubmed/30366943
http://dx.doi.org/10.1083/jcb.201802148