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Pancreatic tumor cell metastasis is restricted by MT1-MMP binding protein MTCBP-1

The process by which tumor cells mechanically invade through surrounding stroma into peripheral tissues is an essential component of metastatic dissemination. The directed recruitment of the metalloproteinase MT1-MMP to invadopodia plays a critical role in this invasive process. Here, we provide mec...

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Detalles Bibliográficos
Autores principales: Qiang, Li, Cao, Hong, Chen, Jing, Weller, Shaun G., Krueger, Eugene W., Zhang, Lizhi, Razidlo, Gina L., McNiven, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314558/
https://www.ncbi.nlm.nih.gov/pubmed/30487181
http://dx.doi.org/10.1083/jcb.201802032