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Bioprinted liver provides early insight into the role of Kupffer cells in TGF-β1 and methotrexate-induced fibrogenesis

Hepatic fibrosis develops from a series of complex interactions among resident and recruited cells making it a challenge to replicate using standard in vitro approaches. While studies have demonstrated the importance of macrophages in fibrogenesis, the role of Kupffer cells (KCs) in modulating the i...

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Detalles Bibliográficos
Autores principales: Norona, Leah M., Nguyen, Deborah G., Gerber, David A., Presnell, Sharon C., Mosedale, Merrie, Watkins, Paul B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314567/
https://www.ncbi.nlm.nih.gov/pubmed/30601836
http://dx.doi.org/10.1371/journal.pone.0208958