Cargando…
Bioprinted liver provides early insight into the role of Kupffer cells in TGF-β1 and methotrexate-induced fibrogenesis
Hepatic fibrosis develops from a series of complex interactions among resident and recruited cells making it a challenge to replicate using standard in vitro approaches. While studies have demonstrated the importance of macrophages in fibrogenesis, the role of Kupffer cells (KCs) in modulating the i...
Autores principales: | Norona, Leah M., Nguyen, Deborah G., Gerber, David A., Presnell, Sharon C., Mosedale, Merrie, Watkins, Paul B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314567/ https://www.ncbi.nlm.nih.gov/pubmed/30601836 http://dx.doi.org/10.1371/journal.pone.0208958 |
Ejemplares similares
-
Proteomic landscape of TGF-β1-induced fibrogenesis in renal fibroblasts
por: Zhou, Shujun, et al.
Publicado: (2020) -
TGF-β in Hepatic Stellate Cell Activation and Liver Fibrogenesis—Updated 2019
por: Dewidar, Bedair, et al.
Publicado: (2019) -
Bioprinted 3D Primary Liver Tissues Allow Assessment of Organ-Level Response to Clinical Drug Induced Toxicity In Vitro
por: Nguyen, Deborah G., et al.
Publicado: (2016) -
Regulatory mechanisms of TGF‐β1‐induced fibrogenesis of human alveolar epithelial cells
por: Shi, Lin, et al.
Publicado: (2016) -
Mechanism of TGF-β1 inhibiting Kupffer cell immune responses in cholestatic cirrhosis
por: Qian, Jun, et al.
Publicado: (2020)