Cargando…
Gd-EOB-DTPA dynamic contrast-enhanced magnetic resonance imaging is more effective than enhanced 64-slice CT for the detection of small lesions in patients with hepatocellular carcinoma
This study aimed to compare the sensitivity and accuracy for the detection of small lesions in patients with hepatocellular carcinoma (HCC) using gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and 64-slice comp...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314721/ https://www.ncbi.nlm.nih.gov/pubmed/30593219 http://dx.doi.org/10.1097/MD.0000000000013964 |
_version_ | 1783384148630568960 |
---|---|
author | Li, Jiangfa Li, Xiaoqing Weng, Jun Lei, Liping Gong, Jianhua Wang, Junyi Li, Zhenghang Zhang, Longmiao He, Songqing |
author_facet | Li, Jiangfa Li, Xiaoqing Weng, Jun Lei, Liping Gong, Jianhua Wang, Junyi Li, Zhenghang Zhang, Longmiao He, Songqing |
author_sort | Li, Jiangfa |
collection | PubMed |
description | This study aimed to compare the sensitivity and accuracy for the detection of small lesions in patients with hepatocellular carcinoma (HCC) using gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and 64-slice computed tomography (CT) enhanced scanning, and to evaluate the necessity to perform MRI in patients diagnosed with HCC by CT. The clinical data from 209 patients with HCC diagnosed prior to surgery in the Affiliated Hospital of Guilin Medical University, China were retrospectively analyzed. The 64-slice dynamic contrast-enhanced multi-detector CT (MDCT) and 3.0 T Gd-EOB-DTPA DCE MRI procedures were successively carried out on all patients who were enrolled in a self-controlled study including detection and diagnosis of HCC lesions by MRI and CT, respectively. A total of 243 lesions were detected and both imaging methods could accurately detect lesions of diameter >2 cm. For lesions <2 cm, MRI detected 47, while CT detected 25 lesions indicating that the detection rate of MRI was 88% higher than that of CT. In addition, MRI detected lesions in 15 cases (7.81% in the total of 209 cases) that were not diagnosed by CT. Among these cases, 2 patients were diagnosed to have no lesion by CT. Gd-EOB-DTPA DCE-MRI performed as a routine check prior to surgery in HCC patients can improve the detection of small HCC lesions. |
format | Online Article Text |
id | pubmed-6314721 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-63147212019-01-14 Gd-EOB-DTPA dynamic contrast-enhanced magnetic resonance imaging is more effective than enhanced 64-slice CT for the detection of small lesions in patients with hepatocellular carcinoma Li, Jiangfa Li, Xiaoqing Weng, Jun Lei, Liping Gong, Jianhua Wang, Junyi Li, Zhenghang Zhang, Longmiao He, Songqing Medicine (Baltimore) Research Article This study aimed to compare the sensitivity and accuracy for the detection of small lesions in patients with hepatocellular carcinoma (HCC) using gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and 64-slice computed tomography (CT) enhanced scanning, and to evaluate the necessity to perform MRI in patients diagnosed with HCC by CT. The clinical data from 209 patients with HCC diagnosed prior to surgery in the Affiliated Hospital of Guilin Medical University, China were retrospectively analyzed. The 64-slice dynamic contrast-enhanced multi-detector CT (MDCT) and 3.0 T Gd-EOB-DTPA DCE MRI procedures were successively carried out on all patients who were enrolled in a self-controlled study including detection and diagnosis of HCC lesions by MRI and CT, respectively. A total of 243 lesions were detected and both imaging methods could accurately detect lesions of diameter >2 cm. For lesions <2 cm, MRI detected 47, while CT detected 25 lesions indicating that the detection rate of MRI was 88% higher than that of CT. In addition, MRI detected lesions in 15 cases (7.81% in the total of 209 cases) that were not diagnosed by CT. Among these cases, 2 patients were diagnosed to have no lesion by CT. Gd-EOB-DTPA DCE-MRI performed as a routine check prior to surgery in HCC patients can improve the detection of small HCC lesions. Wolters Kluwer Health 2018-12-28 /pmc/articles/PMC6314721/ /pubmed/30593219 http://dx.doi.org/10.1097/MD.0000000000013964 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 |
spellingShingle | Research Article Li, Jiangfa Li, Xiaoqing Weng, Jun Lei, Liping Gong, Jianhua Wang, Junyi Li, Zhenghang Zhang, Longmiao He, Songqing Gd-EOB-DTPA dynamic contrast-enhanced magnetic resonance imaging is more effective than enhanced 64-slice CT for the detection of small lesions in patients with hepatocellular carcinoma |
title | Gd-EOB-DTPA dynamic contrast-enhanced magnetic resonance imaging is more effective than enhanced 64-slice CT for the detection of small lesions in patients with hepatocellular carcinoma |
title_full | Gd-EOB-DTPA dynamic contrast-enhanced magnetic resonance imaging is more effective than enhanced 64-slice CT for the detection of small lesions in patients with hepatocellular carcinoma |
title_fullStr | Gd-EOB-DTPA dynamic contrast-enhanced magnetic resonance imaging is more effective than enhanced 64-slice CT for the detection of small lesions in patients with hepatocellular carcinoma |
title_full_unstemmed | Gd-EOB-DTPA dynamic contrast-enhanced magnetic resonance imaging is more effective than enhanced 64-slice CT for the detection of small lesions in patients with hepatocellular carcinoma |
title_short | Gd-EOB-DTPA dynamic contrast-enhanced magnetic resonance imaging is more effective than enhanced 64-slice CT for the detection of small lesions in patients with hepatocellular carcinoma |
title_sort | gd-eob-dtpa dynamic contrast-enhanced magnetic resonance imaging is more effective than enhanced 64-slice ct for the detection of small lesions in patients with hepatocellular carcinoma |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314721/ https://www.ncbi.nlm.nih.gov/pubmed/30593219 http://dx.doi.org/10.1097/MD.0000000000013964 |
work_keys_str_mv | AT lijiangfa gdeobdtpadynamiccontrastenhancedmagneticresonanceimagingismoreeffectivethanenhanced64slicectforthedetectionofsmalllesionsinpatientswithhepatocellularcarcinoma AT lixiaoqing gdeobdtpadynamiccontrastenhancedmagneticresonanceimagingismoreeffectivethanenhanced64slicectforthedetectionofsmalllesionsinpatientswithhepatocellularcarcinoma AT wengjun gdeobdtpadynamiccontrastenhancedmagneticresonanceimagingismoreeffectivethanenhanced64slicectforthedetectionofsmalllesionsinpatientswithhepatocellularcarcinoma AT leiliping gdeobdtpadynamiccontrastenhancedmagneticresonanceimagingismoreeffectivethanenhanced64slicectforthedetectionofsmalllesionsinpatientswithhepatocellularcarcinoma AT gongjianhua gdeobdtpadynamiccontrastenhancedmagneticresonanceimagingismoreeffectivethanenhanced64slicectforthedetectionofsmalllesionsinpatientswithhepatocellularcarcinoma AT wangjunyi gdeobdtpadynamiccontrastenhancedmagneticresonanceimagingismoreeffectivethanenhanced64slicectforthedetectionofsmalllesionsinpatientswithhepatocellularcarcinoma AT lizhenghang gdeobdtpadynamiccontrastenhancedmagneticresonanceimagingismoreeffectivethanenhanced64slicectforthedetectionofsmalllesionsinpatientswithhepatocellularcarcinoma AT zhanglongmiao gdeobdtpadynamiccontrastenhancedmagneticresonanceimagingismoreeffectivethanenhanced64slicectforthedetectionofsmalllesionsinpatientswithhepatocellularcarcinoma AT hesongqing gdeobdtpadynamiccontrastenhancedmagneticresonanceimagingismoreeffectivethanenhanced64slicectforthedetectionofsmalllesionsinpatientswithhepatocellularcarcinoma |