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Elevation of tumor mutation burden in ROS1-fusion lung adenocarcinoma resistant to crizotinib: A case report

RATIONALE: Although most of non-small cell lung cancer (NSCLC) patients with ROS1-fusions respond to crizotinb, acquired resistance eventually develop. The next-generations of ROS1 inhibitors have made some achievements, but the effects of immunotherapy have not been explored. PATIENT CONCERNS: A 44...

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Detalles Bibliográficos
Autores principales:	Yang, Tao, Xu, Rui, Yan, Bing, Li, Fang, Liu, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer Health 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314749/ https://www.ncbi.nlm.nih.gov/pubmed/30593165 http://dx.doi.org/10.1097/MD.0000000000013797

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