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miR-34a is a microRNA safeguard for Citrobacter-induced inflammatory colon oncogenesis
Inflammation often induces regeneration to repair the tissue damage. However, chronic inflammation can transform temporary hyperplasia into a fertile ground for tumorigenesis. Here, we demonstrate that the microRNA miR-34a acts as a central safeguard to protect the inflammatory stem cell niche and r...
Autores principales: | Wang, Lihua, Wang, Ergang, Wang, Yi, Mines, Robert, Xiang, Kun, Sun, Zhiguo, Zhou, Gaiting, Chen, Kai-Yuan, Rakhilin, Nikolai, Chao, Shanshan, Ye, Gaoqi, Wu, Zhenzhen, Yan, Huiwen, Shen, Hong, Everitt, Jeffrey, Bu, Pengcheng, Shen, Xiling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314783/ https://www.ncbi.nlm.nih.gov/pubmed/30543324 http://dx.doi.org/10.7554/eLife.39479 |
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