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Genetic and pharmacological interventions in the aging motor nervous system slow motor aging and extend life span in C. elegans
As animals and humans age, the motor system undergoes a progressive functional decline, leading to frailty. Age-dependent functional deteriorations at neuromuscular junctions (NMJs) contribute to this motor aging. However, it is unclear whether one can intervene in this process to slow motor aging....
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314820/ https://www.ncbi.nlm.nih.gov/pubmed/30613772 http://dx.doi.org/10.1126/sciadv.aau5041 |