Genetic and pharmacological interventions in the aging motor nervous system slow motor aging and extend life span in C. elegans

As animals and humans age, the motor system undergoes a progressive functional decline, leading to frailty. Age-dependent functional deteriorations at neuromuscular junctions (NMJs) contribute to this motor aging. However, it is unclear whether one can intervene in this process to slow motor aging....

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Detalles Bibliográficos
Autores principales: Li, Guang, Gong, Jianke, Liu, Jie, Liu, Jinzhi, Li, Huahua, Hsu, Ao-Lin, Liu, Jianfeng, Xu, X.Z. Shawn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314820/
https://www.ncbi.nlm.nih.gov/pubmed/30613772
http://dx.doi.org/10.1126/sciadv.aau5041

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