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Novel Adult-Onset Systolic Cardiomyopathy Due to MYH7 E848G Mutation in Patient-Derived Induced Pluripotent Stem Cells

A novel myosin heavy chain 7 mutation (E848G) identified in a familial cardiomyopathy was studied in patient-specific induced pluripotent stem cell–derived cardiomyocytes. The cardiomyopathic human induced pluripotent stem cell–derived cardiomyocytes exhibited reduced contractile function as single...

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Detalles Bibliográficos
Autores principales:	Yang, Kai-Chun, Breitbart, Astrid, De Lange, Willem J., Hofsteen, Peter, Futakuchi-Tsuchida, Akiko, Xu, Joy, Schopf, Cody, Razumova, Maria V., Jiao, Alex, Boucek, Robert, Pabon, Lil, Reinecke, Hans, Kim, Deok-Ho, Ralphe, J. Carter, Regnier, Michael, Murry, Charles E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	PRECLINICAL RESEARCH
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314962/ https://www.ncbi.nlm.nih.gov/pubmed/30623132 http://dx.doi.org/10.1016/j.jacbts.2018.08.008

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