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Detecting topological variations of DNA at single-molecule level

In addition to their use in DNA sequencing, ultrathin nanopore membranes have potential applications in detecting topological variations in deoxyribonucleic acid (DNA). This is due to the fact that when topologically edited DNA molecules, driven by electrophoretic forces, translocate through a narro...

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Detalles Bibliográficos
Autores principales: Liu, Ke, Pan, Chao, Kuhn, Alexandre, Nievergelt, Adrian Pascal, Fantner, Georg E., Milenkovic, Olgica, Radenovic, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315031/
https://www.ncbi.nlm.nih.gov/pubmed/30602774
http://dx.doi.org/10.1038/s41467-018-07924-1