A Protective Monoclonal Antibody Targets a Site of Vulnerability on the Surface of Rift Valley Fever Virus

The Gn subcomponent of the Gn-Gc assembly that envelopes the human and animal pathogen, Rift Valley fever virus (RVFV), is a primary target of the neutralizing antibody response. To better understand the molecular basis for immune recognition, we raised a class of neutralizing monoclonal antibodies...

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Detalles Bibliográficos
Autores principales: Allen, Elizabeth R., Krumm, Stefanie A., Raghwani, Jayna, Halldorsson, Steinar, Elliott, Angela, Graham, Victoria A., Koudriakova, Elina, Harlos, Karl, Wright, Daniel, Warimwe, George M., Brennan, Benjamin, Huiskonen, Juha T., Dowall, Stuart D., Elliott, Richard M., Pybus, Oliver G., Burton, Dennis R., Hewson, Roger, Doores, Katie J., Bowden, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315105/
https://www.ncbi.nlm.nih.gov/pubmed/30590046
http://dx.doi.org/10.1016/j.celrep.2018.12.001

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