Cargando…

Mechanisms of Tumor-Induced Lymphovascular Niche Formation in Draining Lymph Nodes

Enlargement of the lymphatic vascular network in tumor-draining lymph nodes (LNs) often precedes LN metastasis, likely providing a lymphovascular niche for tumor cells. We investigated morphological and molecular changes associated with the lymphatic remodeling process, using the 4T1 breast cancer a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Commerford, Catharina D., Dieterich, Lothar C., He, Yuliang, Hell, Tanja, Montoya-Zegarra, Javier A., Noerrelykke, Simon F., Russo, Erica, Röcken, Martin, Detmar, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315107/ https://www.ncbi.nlm.nih.gov/pubmed/30590031 http://dx.doi.org/10.1016/j.celrep.2018.12.002

Ejemplares similares

Immunomodulatory Responses of Subcapsular Sinus Floor Lymphatic Endothelial Cells in Tumor-Draining Lymph Nodes
por: Sibler, Eliane, et al.
Publicado: (2022)

A Distinct Role of the Autonomic Nervous System in Modulating the Function of Lymphatic Vessels under Physiological and Tumor-Draining Conditions
por: Bachmann, Samia B., et al.
Publicado: (2019)

Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes
por: Fujimoto, Noriki, et al.
Publicado: (2020)

Single-Cell Transcriptional Heterogeneity of Lymphatic Endothelial Cells in Normal and Inflamed Murine Lymph Nodes
por: Sibler, Eliane, et al.
Publicado: (2021)

Melanoma‐derived extracellular vesicles mediate lymphatic remodelling and impair tumour immunity in draining lymph nodes
por: Leary, Noelle, et al.
Publicado: (2022)

Unlocking the therapeutic potential of primary tumor-draining lymph nodes
por: Rotman, Jossie, et al.
Publicado: (2019)

slanDCs in carcinoma-draining lymph nodes
por: Vermi, William, et al.
Publicado: (2014)

Transcriptional profiling of breast cancer‐associated lymphatic vessels reveals VCAM‐1 as regulator of lymphatic invasion and permeability
por: Dieterich, Lothar C., et al.
Publicado: (2019)

The pre-metastatic niche in lymph nodes: formation and characteristics
por: Gillot, Lionel, et al.
Publicado: (2021)

Increased Expression of ATG10 in Colorectal Cancer Is Associated with Lymphovascular Invasion and Lymph Node Metastasis
por: Jo, Yoon Kyung, et al.
Publicado: (2012)

Lymphovascular or perineural invasion is associated with lymph node metastasis and survival outcomes in patients with gastric cancer
por: Zhang, Fengxiang, et al.
Publicado: (2023)

Immune Checkpoint Therapy: Tumor Draining Lymph Nodes in the Spotlights
por: Fransen, Marieke F., et al.
Publicado: (2021)

STUDIES OF THE CELLS IN THE AFFERENT AND EFFERENT LYMPH OF LYMPH NODES DRAINING THE SITE OF SKIN HOMOGRAFTS
por: Hall, J. G.
Publicado: (1967)

Impact of lymphovascular invasion on lymph node metastasis for patients undergoing radical prostatectomy with negative resection margin
por: Kang, Yong Jin, et al.
Publicado: (2017)

Prognostic value of lymphovascular invasion in stage II colorectal cancer patients with an inadequate examination of lymph nodes
por: Gao, Zhenyan, et al.
Publicado: (2021)

Risk Factors for Lymph Node Metastasis and Oncologic Outcomes in Small Rectal Neuroendocrine Tumors with Lymphovascular Invasion
por: Nam, Seung-Joo, et al.
Publicado: (2022)

Reconstruction of Immune Microenvironment and Signaling Pathways in Endometrioid Endometrial Adenocarcinoma During Formation of Lymphovascular Space Involvement and Lymph Node Metastasis
por: Cheng, Yuan, et al.
Publicado: (2020)

The Premetastatic Lymph Node Niche in Gynecologic Cancer
por: Karpathiou, Georgia, et al.
Publicado: (2023)

A new predictive model combined of tumor size, lymph nodes count and lymphovascular invasion for survival prognosis in patients with lymph node-negative gastric cancer
por: Zhao, Lin-Yong, et al.
Publicado: (2016)

Immunological significance of the morphological changes in lymph nodes draining breast cancer.
por: Anastassiades, O. T., et al.
Publicado: (1966)

Reactions in Lymph Nodes Draining X-Irradiated and Carcinogen Treated Tissues
por: Marshall, A. H. E.
Publicado: (1956)

The Draining Lymph Node in Rheumatoid Arthritis: Current Concepts and Research Perspectives
por: Benaglio, Francesca, et al.
Publicado: (2015)

Comparative evaluation of T-cell receptors in experimental glioma-draining lymph nodes
por: Blobner, Jens, et al.
Publicado: (2021)

Kidney-Draining Lymph Node Fibrosis Following Unilateral Ureteral Obstruction
por: Li, Xiaofei, et al.
Publicado: (2021)

39607 Mapping the Draining Lymph Nodes in Central Nervous System Malignancies
por: Coxon, Andrew T., et al.
Publicado: (2021)

Tumor-Draining Lymph Secretome En Route to the Regional Lymph Node in Breast Cancer Metastasis
por: Mohammed, Sulma I, et al.
Publicado: (2020)

The Role of Lymphovascular Invasion as a Prognostic Factor in Patients with Lymph Node-Positive Operable Invasive Breast Cancer
por: Song, Young Ju, et al.
Publicado: (2011)

Lymph node metastasis and pattern of recurrence in clinically early stage endometrial cancer with positive lymphovascular space invasion
por: Mahdi, Haider, et al.
Publicado: (2015)

Relationship of lymphovascular invasion with lymph node metastasis and prognosis in superficial esophageal carcinoma: systematic review and meta-analysis
por: Yang, Jinxin, et al.
Publicado: (2020)

What is the prognostic importance of lymphovascular space invasion in the absence of lymph node metastasis for early-stage endometrial cancer?
por: Aslan, Koray, et al.
Publicado: (2021)

Prognosis value of lymphovascular invasion in patients with invasive ductal breast carcinoma according to lymph node metastasis status
por: da Luz, Felipe Andrés Cordero, et al.
Publicado: (2022)

Metinel Node—The First Lymph Node Draining a Metastasis—Contains Tumor-Reactive Lymphocytes
por: Dahl, Kjell, et al.
Publicado: (2008)

High PD-1 expression on regulatory and effector T-cells in lung cancer draining lymph nodes
por: van de Ven, Rieneke, et al.
Publicado: (2017)

Using lymph node transplantation as an approach to image cellular interactions between the skin and draining lymph nodes during parasitic infections()()
por: Lawton, Jennifer C., et al.
Publicado: (2014)

Microenvironment of Tumor-Draining Lymph Nodes: Opportunities for Liposome-Based Targeted Therapy
por: Chandrasekaran, Siddarth, et al.
Publicado: (2014)

COX-2 Inhibition Reduces Brucella Bacterial Burden in Draining Lymph Nodes
por: Gagnaire, Aurélie, et al.
Publicado: (2016)

Characterization of Antigen-Presenting Cell Subsets in Human Liver-Draining Lymph Nodes
por: Boor, Patrick P. C., et al.
Publicado: (2019)

Vaccine-draining lymph nodes of cancer patients for generating anti-cancer antibodies
por: Shukla, Girja S., et al.
Publicado: (2017)

Chemotherapy but Not the Tumor Draining Lymph Nodes Determine the Immunotherapy Response in Secondary Tumors
por: Zhao, Xianda, et al.
Publicado: (2020)

Suction Drain Volume following Axillary Lymph Node Dissection for Melanoma—When to Remove Drains? A Retrospective Cohort Study
por: Winter, Raimund, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_fm7rb3id7d50lk99i614urt1in