Culling Less Fit Neurons Protects against Amyloid-β-Induced Brain Damage and Cognitive and Motor Decline

Alzheimer’s disease (AD) is the most common form of dementia, impairing cognitive and motor functions. One of the pathological hallmarks of AD is neuronal loss, which is not reflected in mouse models of AD. Therefore, the role of neuronal death is still uncertain. Here, we used a Drosophila AD model...

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Detalles Bibliográficos
Autores principales: Coelho, Dina S., Schwartz, Silvia, Merino, Marisa M., Hauert, Barbara, Topfel, Barbara, Tieche, Colin, Rhiner, Christa, Moreno, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315112/
https://www.ncbi.nlm.nih.gov/pubmed/30590040
http://dx.doi.org/10.1016/j.celrep.2018.11.098

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