Mycobacterium leprae Recombinant Antigen Induces High Expression of Multifunction T Lymphocytes and Is Promising as a Specific Vaccine for Leprosy

Leprosy is a chronic disease caused by M. leprae infection that can cause severe neurological complications and physical disabilities. A leprosy-specific vaccine would be an important component within control programs but is still lacking. Given that multifunctional CD4 T cells [i.e., those capable...

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Detalles Bibliográficos
Autores principales: Bezerra-Santos, Márcio, do Vale-Simon, Marise, Barreto, Aline Silva, Cazzaniga, Rodrigo Anselmo, de Oliveira, Daniela Teles, Barrios, Mônica Rueda, Ferreira, Alex Ricardo, Santos-Bio, Nanci C., Reed, Steven G., de Almeida, Roque Pacheco, Corrêa, Cristiane Bani, Duthie, Malcolm S., de Jesus, Amélia Ribeiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315144/
https://www.ncbi.nlm.nih.gov/pubmed/30631322
http://dx.doi.org/10.3389/fimmu.2018.02920

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