Candida auris: What Have We Learned About Its Mechanisms of Pathogenicity?

Candida auris has emerged globally as a multidrug-resistant (MDR) medical care-associated fungal pathogen. Recent reports have demonstrated that C. auris usually expresses fewer virulence factors than does Candida albicans. However, the tendency of C. auris transmission within and between healthcare...

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Detalles Bibliográficos
Autores principales: Rossato, Luana, Colombo, Arnaldo Lopes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315175/
https://www.ncbi.nlm.nih.gov/pubmed/30631313
http://dx.doi.org/10.3389/fmicb.2018.03081
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author Rossato, Luana
Colombo, Arnaldo Lopes
author_facet Rossato, Luana
Colombo, Arnaldo Lopes
author_sort Rossato, Luana
collection PubMed
description Candida auris has emerged globally as a multidrug-resistant (MDR) medical care-associated fungal pathogen. Recent reports have demonstrated that C. auris usually expresses fewer virulence factors than does Candida albicans. However, the tendency of C. auris transmission within and between healthcare facilities is unique among Candida spp. and is possibly promoted by virulence and pathogenicity factors that facilitate skin colonization and environmental persistence. To understand the ability of this yeast to cause disease, we herein discuss several virulence and pathogenicity aspects of C. auris.
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spelling pubmed-63151752019-01-10 Candida auris: What Have We Learned About Its Mechanisms of Pathogenicity? Rossato, Luana Colombo, Arnaldo Lopes Front Microbiol Microbiology Candida auris has emerged globally as a multidrug-resistant (MDR) medical care-associated fungal pathogen. Recent reports have demonstrated that C. auris usually expresses fewer virulence factors than does Candida albicans. However, the tendency of C. auris transmission within and between healthcare facilities is unique among Candida spp. and is possibly promoted by virulence and pathogenicity factors that facilitate skin colonization and environmental persistence. To understand the ability of this yeast to cause disease, we herein discuss several virulence and pathogenicity aspects of C. auris. Frontiers Media S.A. 2018-12-12 /pmc/articles/PMC6315175/ /pubmed/30631313 http://dx.doi.org/10.3389/fmicb.2018.03081 Text en Copyright © 2018 Rossato and Colombo. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Rossato, Luana
Colombo, Arnaldo Lopes
Candida auris: What Have We Learned About Its Mechanisms of Pathogenicity?
title Candida auris: What Have We Learned About Its Mechanisms of Pathogenicity?
title_full Candida auris: What Have We Learned About Its Mechanisms of Pathogenicity?
title_fullStr Candida auris: What Have We Learned About Its Mechanisms of Pathogenicity?
title_full_unstemmed Candida auris: What Have We Learned About Its Mechanisms of Pathogenicity?
title_short Candida auris: What Have We Learned About Its Mechanisms of Pathogenicity?
title_sort candida auris: what have we learned about its mechanisms of pathogenicity?
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315175/
https://www.ncbi.nlm.nih.gov/pubmed/30631313
http://dx.doi.org/10.3389/fmicb.2018.03081
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