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Structure-Guided Mechanisms Behind the Metabolism of 2,4,6-Trinitrotoluene by Glutathione Transferases U25 and U24 That Lead to Alternate Product Distribution

The explosive xenobiotic 2,4,6-trinitrotoluene (TNT) is a major worldwide environmental pollutant and its persistence in the environment presents health and environmental concerns. The chemical structure of TNT dictates that biological detoxification pathways follow predominantly reductive transform...

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Detalles Bibliográficos
Autores principales:	Tzafestas, Kyriakos, Ahmad, Laziana, Dani, M. Paulina, Grogan, Gideon, Rylott, Elizabeth L., Bruce, Neil C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Plant Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315187/ https://www.ncbi.nlm.nih.gov/pubmed/30631331 http://dx.doi.org/10.3389/fpls.2018.01846

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