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Simvastatin Reduces Neutrophils Infiltration Into Brain Parenchyma After Intracerebral Hemorrhage via Regulating Peripheral Neutrophils Apoptosis
Statins, known for their lipid-lowering effects, also have immunomodulatory properties. This study aims to examine whether systematic simvastatin administration could decrease polymorphonuclear neutrophils (PMNs) infiltration into brain tissue, as well as alleviate neuroinflammation in a rat model o...
Autores principales: | Zhang, Jianbo, Shi, Xia, Hao, Na, Chen, Zhi, Wei, Linjie, Tan, Liang, Chen, Yujie, Feng, Hua, Chen, Qianwei, Zhu, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315192/ https://www.ncbi.nlm.nih.gov/pubmed/30631264 http://dx.doi.org/10.3389/fnins.2018.00977 |
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