An Integrative Study of Protein-RNA Condensates Identifies Scaffolding RNAs and Reveals Players in Fragile X-Associated Tremor/Ataxia Syndrome

Recent evidence indicates that specific RNAs promote the formation of ribonucleoprotein condensates by acting as scaffolds for RNA-binding proteins (RBPs). We systematically investigated RNA-RBP interaction networks to understand ribonucleoprotein assembly. We found that highly contacted RNAs are st...

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Detalles Bibliográficos
Autores principales: Cid-Samper, Fernando, Gelabert-Baldrich, Mariona, Lang, Benjamin, Lorenzo-Gotor, Nieves, Ponti, Riccardo Delli, Severijnen, Lies-Anne W.F.M., Bolognesi, Benedetta, Gelpi, Ellen, Hukema, Renate K., Botta-Orfila, Teresa, Tartaglia, Gian Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315285/
https://www.ncbi.nlm.nih.gov/pubmed/30566867
http://dx.doi.org/10.1016/j.celrep.2018.11.076

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