Cargando…

Risk Factors for Surgical Site Infection after Soft-Tissue Sarcoma Resection, Including the Preoperative Geriatric Nutritional Risk Index

Malignant soft-tissue sarcoma resection is associated with a relatively high incidence of surgical site infection (SSI). The known risk factors for SSI following soft-tissue sarcoma resection include tumor size and location, prolonged surgery, and massive blood loss. The geriatric nutritional risk i...

Descripción completa

Detalles Bibliográficos
Autores principales: Sasaki, Hiromi, Nagano, Satoshi, Taniguchi, Noboru, Setoguchi, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315374/
https://www.ncbi.nlm.nih.gov/pubmed/30513989
http://dx.doi.org/10.3390/nu10121900
_version_ 1783384279245389824
author Sasaki, Hiromi
Nagano, Satoshi
Taniguchi, Noboru
Setoguchi, Takao
author_facet Sasaki, Hiromi
Nagano, Satoshi
Taniguchi, Noboru
Setoguchi, Takao
author_sort Sasaki, Hiromi
collection PubMed
description Malignant soft-tissue sarcoma resection is associated with a relatively high incidence of surgical site infection (SSI). The known risk factors for SSI following soft-tissue sarcoma resection include tumor size and location, prolonged surgery, and massive blood loss. The geriatric nutritional risk index (GNRI) was used as a tool to help predict the occurrence of SSI after major surgery. We investigated the utility of the GNRI as a predictor of SSI following soft-tissue sarcoma resection. We retrospectively reviewed 152 patients who underwent surgical resection of soft-tissue sarcoma in our institute, and found that the incidence of SSI was 18.4% (28/152). The SSI and non-SSI groups significantly differed regarding surgical time, diameter of the skin incision, maximum tumor diameter, instrumentation, presence of an open wound, preoperative chemotherapy, preoperative C-reactive protein concentration, and GNRI. Binomial logistic regression analysis showed that the risk factors for SSI following soft-tissue sarcoma surgery were male sex, larger skin incision diameter, larger maximum tumor diameter, presence of an open wound, and lower GNRI. Our findings indicate that malnutrition is a risk factor for SSI after soft-tissue sarcoma resection, and suggest that appropriate assessment and intervention for malnutrition may reduce the incidence of SSI.
format Online
Article
Text
id pubmed-6315374
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-63153742019-01-08 Risk Factors for Surgical Site Infection after Soft-Tissue Sarcoma Resection, Including the Preoperative Geriatric Nutritional Risk Index Sasaki, Hiromi Nagano, Satoshi Taniguchi, Noboru Setoguchi, Takao Nutrients Article Malignant soft-tissue sarcoma resection is associated with a relatively high incidence of surgical site infection (SSI). The known risk factors for SSI following soft-tissue sarcoma resection include tumor size and location, prolonged surgery, and massive blood loss. The geriatric nutritional risk index (GNRI) was used as a tool to help predict the occurrence of SSI after major surgery. We investigated the utility of the GNRI as a predictor of SSI following soft-tissue sarcoma resection. We retrospectively reviewed 152 patients who underwent surgical resection of soft-tissue sarcoma in our institute, and found that the incidence of SSI was 18.4% (28/152). The SSI and non-SSI groups significantly differed regarding surgical time, diameter of the skin incision, maximum tumor diameter, instrumentation, presence of an open wound, preoperative chemotherapy, preoperative C-reactive protein concentration, and GNRI. Binomial logistic regression analysis showed that the risk factors for SSI following soft-tissue sarcoma surgery were male sex, larger skin incision diameter, larger maximum tumor diameter, presence of an open wound, and lower GNRI. Our findings indicate that malnutrition is a risk factor for SSI after soft-tissue sarcoma resection, and suggest that appropriate assessment and intervention for malnutrition may reduce the incidence of SSI. MDPI 2018-12-03 /pmc/articles/PMC6315374/ /pubmed/30513989 http://dx.doi.org/10.3390/nu10121900 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sasaki, Hiromi
Nagano, Satoshi
Taniguchi, Noboru
Setoguchi, Takao
Risk Factors for Surgical Site Infection after Soft-Tissue Sarcoma Resection, Including the Preoperative Geriatric Nutritional Risk Index
title Risk Factors for Surgical Site Infection after Soft-Tissue Sarcoma Resection, Including the Preoperative Geriatric Nutritional Risk Index
title_full Risk Factors for Surgical Site Infection after Soft-Tissue Sarcoma Resection, Including the Preoperative Geriatric Nutritional Risk Index
title_fullStr Risk Factors for Surgical Site Infection after Soft-Tissue Sarcoma Resection, Including the Preoperative Geriatric Nutritional Risk Index
title_full_unstemmed Risk Factors for Surgical Site Infection after Soft-Tissue Sarcoma Resection, Including the Preoperative Geriatric Nutritional Risk Index
title_short Risk Factors for Surgical Site Infection after Soft-Tissue Sarcoma Resection, Including the Preoperative Geriatric Nutritional Risk Index
title_sort risk factors for surgical site infection after soft-tissue sarcoma resection, including the preoperative geriatric nutritional risk index
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315374/
https://www.ncbi.nlm.nih.gov/pubmed/30513989
http://dx.doi.org/10.3390/nu10121900
work_keys_str_mv AT sasakihiromi riskfactorsforsurgicalsiteinfectionaftersofttissuesarcomaresectionincludingthepreoperativegeriatricnutritionalriskindex
AT naganosatoshi riskfactorsforsurgicalsiteinfectionaftersofttissuesarcomaresectionincludingthepreoperativegeriatricnutritionalriskindex
AT taniguchinoboru riskfactorsforsurgicalsiteinfectionaftersofttissuesarcomaresectionincludingthepreoperativegeriatricnutritionalriskindex
AT setoguchitakao riskfactorsforsurgicalsiteinfectionaftersofttissuesarcomaresectionincludingthepreoperativegeriatricnutritionalriskindex