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Mechanisms of Matrix-Induced Chemoresistance of Breast Cancer Cells—Deciphering Novel Potential Targets for a Cell Sensitization

Tumor cell binding to microenvironment components such as collagen type 1 (COL1) attenuates the sensitivity to cytotoxic drugs like cisplatin (CDDP) or mitoxantrone (MX), referred to as cell adhesion mediated drug resistance (CAM-DR). CAM-DR is considered as the onset for resistance mutations, but u...

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Detalles Bibliográficos
Autores principales:	Jakubzig, Bastian, Baltes, Fabian, Henze, Svenja, Schlesinger, Martin, Bendas, Gerd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315379/ https://www.ncbi.nlm.nih.gov/pubmed/30563275 http://dx.doi.org/10.3390/cancers10120495

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