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Quality of Dietary Fat Intake and Body Weight and Obesity in a Mediterranean Population: Secondary Analyses within the PREDIMED Trial
A moderately high-fat Mediterranean diet does not promote weight gain. This study aimed to investigate the association between dietary intake of specific types of fat and obesity and body weight. A prospective cohort study was performed using data of 6942 participants in the PREDIMED trial, with yea...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315420/ https://www.ncbi.nlm.nih.gov/pubmed/30572588 http://dx.doi.org/10.3390/nu10122011 |
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author | Beulen, Yvette Martínez-González, Miguel A. van de Rest, Ondine Salas-Salvadó, Jordi Sorlí, José V. Gómez-Gracia, Enrique Fiol, Miquel Estruch, Ramón Santos-Lozano, José M. Schröder, Helmut Alonso-Gómez, Angel Serra-Majem, Luis Pintó, Xavier Ros, Emilio Becerra-Tomas, Nerea González, José I. Fitó, Montserrat Martínez, J. Alfredo. Gea, Alfredo |
author_facet | Beulen, Yvette Martínez-González, Miguel A. van de Rest, Ondine Salas-Salvadó, Jordi Sorlí, José V. Gómez-Gracia, Enrique Fiol, Miquel Estruch, Ramón Santos-Lozano, José M. Schröder, Helmut Alonso-Gómez, Angel Serra-Majem, Luis Pintó, Xavier Ros, Emilio Becerra-Tomas, Nerea González, José I. Fitó, Montserrat Martínez, J. Alfredo. Gea, Alfredo |
author_sort | Beulen, Yvette |
collection | PubMed |
description | A moderately high-fat Mediterranean diet does not promote weight gain. This study aimed to investigate the association between dietary intake of specific types of fat and obesity and body weight. A prospective cohort study was performed using data of 6942 participants in the PREDIMED trial, with yearly repeated validated food-frequency questionnaires, and anthropometric outcomes (median follow-up: 4.8 years). The effects of replacing dietary fat subtypes for one another, proteins or carbohydrates were estimated using generalized estimating equations substitution models. Replacement of 5% energy from saturated fatty acids (SFA) with monounsaturated fatty acids (MUFA) or polyunsaturated fatty acids (PUFA) resulted in weight changes of −0.38 kg (95% Confidece Iinterval (CI): −0.69, −0.07), and −0.51 kg (95% CI: −0.81, −0.20), respectively. Replacing proteins with MUFA or PUFA decreased the odds of becoming obese. Estimates for the daily substitution of one portion of red meat with white meat, oily fish or white fish showed weight changes up to −0.87 kg. Increasing the intake of unsaturated fatty acids at the expense of SFA, proteins, and carbohydrates showed beneficial effects on body weight and obesity. It may therefore be desirable to encourage high-quality fat diets like the Mediterranean diet instead of restricting total fat intake. |
format | Online Article Text |
id | pubmed-6315420 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-63154202019-01-08 Quality of Dietary Fat Intake and Body Weight and Obesity in a Mediterranean Population: Secondary Analyses within the PREDIMED Trial Beulen, Yvette Martínez-González, Miguel A. van de Rest, Ondine Salas-Salvadó, Jordi Sorlí, José V. Gómez-Gracia, Enrique Fiol, Miquel Estruch, Ramón Santos-Lozano, José M. Schröder, Helmut Alonso-Gómez, Angel Serra-Majem, Luis Pintó, Xavier Ros, Emilio Becerra-Tomas, Nerea González, José I. Fitó, Montserrat Martínez, J. Alfredo. Gea, Alfredo Nutrients Article A moderately high-fat Mediterranean diet does not promote weight gain. This study aimed to investigate the association between dietary intake of specific types of fat and obesity and body weight. A prospective cohort study was performed using data of 6942 participants in the PREDIMED trial, with yearly repeated validated food-frequency questionnaires, and anthropometric outcomes (median follow-up: 4.8 years). The effects of replacing dietary fat subtypes for one another, proteins or carbohydrates were estimated using generalized estimating equations substitution models. Replacement of 5% energy from saturated fatty acids (SFA) with monounsaturated fatty acids (MUFA) or polyunsaturated fatty acids (PUFA) resulted in weight changes of −0.38 kg (95% Confidece Iinterval (CI): −0.69, −0.07), and −0.51 kg (95% CI: −0.81, −0.20), respectively. Replacing proteins with MUFA or PUFA decreased the odds of becoming obese. Estimates for the daily substitution of one portion of red meat with white meat, oily fish or white fish showed weight changes up to −0.87 kg. Increasing the intake of unsaturated fatty acids at the expense of SFA, proteins, and carbohydrates showed beneficial effects on body weight and obesity. It may therefore be desirable to encourage high-quality fat diets like the Mediterranean diet instead of restricting total fat intake. MDPI 2018-12-19 /pmc/articles/PMC6315420/ /pubmed/30572588 http://dx.doi.org/10.3390/nu10122011 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Beulen, Yvette Martínez-González, Miguel A. van de Rest, Ondine Salas-Salvadó, Jordi Sorlí, José V. Gómez-Gracia, Enrique Fiol, Miquel Estruch, Ramón Santos-Lozano, José M. Schröder, Helmut Alonso-Gómez, Angel Serra-Majem, Luis Pintó, Xavier Ros, Emilio Becerra-Tomas, Nerea González, José I. Fitó, Montserrat Martínez, J. Alfredo. Gea, Alfredo Quality of Dietary Fat Intake and Body Weight and Obesity in a Mediterranean Population: Secondary Analyses within the PREDIMED Trial |
title | Quality of Dietary Fat Intake and Body Weight and Obesity in a Mediterranean Population: Secondary Analyses within the PREDIMED Trial |
title_full | Quality of Dietary Fat Intake and Body Weight and Obesity in a Mediterranean Population: Secondary Analyses within the PREDIMED Trial |
title_fullStr | Quality of Dietary Fat Intake and Body Weight and Obesity in a Mediterranean Population: Secondary Analyses within the PREDIMED Trial |
title_full_unstemmed | Quality of Dietary Fat Intake and Body Weight and Obesity in a Mediterranean Population: Secondary Analyses within the PREDIMED Trial |
title_short | Quality of Dietary Fat Intake and Body Weight and Obesity in a Mediterranean Population: Secondary Analyses within the PREDIMED Trial |
title_sort | quality of dietary fat intake and body weight and obesity in a mediterranean population: secondary analyses within the predimed trial |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315420/ https://www.ncbi.nlm.nih.gov/pubmed/30572588 http://dx.doi.org/10.3390/nu10122011 |
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