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Transporter and Lysosomal Mediated (Multi)drug Resistance to Tyrosine Kinase Inhibitors and Potential Strategies to Overcome Resistance

Tyrosine kinase inhibitors are a class of chemotherapeutic drugs that target specific protein kinases. These tyrosine kinase inhibitors constitute a relatively new class of drugs which target for instance Bcr-Abl, Epidermal Growth Factor Receptor (EGFR) and Vascular Endothelial Growth Factor Recepto...

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Detalles Bibliográficos
Autores principales: de Klerk, Daniel J., Honeywell, Richard J., Jansen, Gerrit, Peters, Godefridus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315453/
https://www.ncbi.nlm.nih.gov/pubmed/30544701
http://dx.doi.org/10.3390/cancers10120503