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Comparative Assessment of Tungsten Toxicity in the Absence or Presence of Other Metals

Tungsten is a refractory metal that is used in a wide range of applications. It was initially perceived that tungsten was immobile in the environment, supporting tungsten as an alternative for lead and uranium in munition and military applications. Recent studies report movement and detection of tun...

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Autores principales: Wasel, Ola, Freeman, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315525/
https://www.ncbi.nlm.nih.gov/pubmed/30423906
http://dx.doi.org/10.3390/toxics6040066
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author Wasel, Ola
Freeman, Jennifer L.
author_facet Wasel, Ola
Freeman, Jennifer L.
author_sort Wasel, Ola
collection PubMed
description Tungsten is a refractory metal that is used in a wide range of applications. It was initially perceived that tungsten was immobile in the environment, supporting tungsten as an alternative for lead and uranium in munition and military applications. Recent studies report movement and detection of tungsten in soil and potable water sources, increasing the risk of human exposure. In addition, experimental research studies observed adverse health effects associated with exposure to tungsten alloys, raising concerns on tungsten toxicity with questions surrounding the safety of exposure to tungsten alone or in mixtures with other metals. Tungsten is commonly used as an alloy with nickel and cobalt in many applications to adjust hardness and thermal and electrical conductivity. This review addresses the current state of knowledge in regard to the mechanisms of toxicity of tungsten in the absence or presence of other metals with a specific focus on mixtures containing nickel and cobalt, the most common components of tungsten alloy.
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spelling pubmed-63155252019-01-11 Comparative Assessment of Tungsten Toxicity in the Absence or Presence of Other Metals Wasel, Ola Freeman, Jennifer L. Toxics Review Tungsten is a refractory metal that is used in a wide range of applications. It was initially perceived that tungsten was immobile in the environment, supporting tungsten as an alternative for lead and uranium in munition and military applications. Recent studies report movement and detection of tungsten in soil and potable water sources, increasing the risk of human exposure. In addition, experimental research studies observed adverse health effects associated with exposure to tungsten alloys, raising concerns on tungsten toxicity with questions surrounding the safety of exposure to tungsten alone or in mixtures with other metals. Tungsten is commonly used as an alloy with nickel and cobalt in many applications to adjust hardness and thermal and electrical conductivity. This review addresses the current state of knowledge in regard to the mechanisms of toxicity of tungsten in the absence or presence of other metals with a specific focus on mixtures containing nickel and cobalt, the most common components of tungsten alloy. MDPI 2018-11-09 /pmc/articles/PMC6315525/ /pubmed/30423906 http://dx.doi.org/10.3390/toxics6040066 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Wasel, Ola
Freeman, Jennifer L.
Comparative Assessment of Tungsten Toxicity in the Absence or Presence of Other Metals
title Comparative Assessment of Tungsten Toxicity in the Absence or Presence of Other Metals
title_full Comparative Assessment of Tungsten Toxicity in the Absence or Presence of Other Metals
title_fullStr Comparative Assessment of Tungsten Toxicity in the Absence or Presence of Other Metals
title_full_unstemmed Comparative Assessment of Tungsten Toxicity in the Absence or Presence of Other Metals
title_short Comparative Assessment of Tungsten Toxicity in the Absence or Presence of Other Metals
title_sort comparative assessment of tungsten toxicity in the absence or presence of other metals
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315525/
https://www.ncbi.nlm.nih.gov/pubmed/30423906
http://dx.doi.org/10.3390/toxics6040066
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