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Nile Tilapia Derived Antimicrobial Peptide TP4 Exerts Antineoplastic Activity Through Microtubule Disruption

Some antimicrobial peptides (AMPs) exhibit anti-cancer activity, acting on cancer cells either by causing membrane lysis or via intracellular effects. While intracellular penetration of AMPs has been shown to cause cancer cell death, the mechanisms of toxicity remain largely unknown. Here we show th...

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Detalles Bibliográficos
Autores principales: Ting, Chen-Hung, Liu, Yi-Chung, Lyu, Ping-Chiang, Chen, Jyh-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315541/
https://www.ncbi.nlm.nih.gov/pubmed/30469546
http://dx.doi.org/10.3390/md16120462