A Diffusion-Based pH Regulator in Laminar Flows with Smartphone-Based Colorimetric Analysis

A strategy for an on-chip pH regulator is demonstrated computationally and experimentally, based on the diffusion characteristics of aqueous ionic solutions. Micro-flows with specific pH values are formed based on the diffusion behaviors of hydrogen and hydroxide ions in laminar flows. The final ach...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Zeng, Zhi, Xu, Wei, Wu, Wenming, Liang, Wenfeng, Zhou, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315573/
https://www.ncbi.nlm.nih.gov/pubmed/30477093
http://dx.doi.org/10.3390/mi9120616
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author Wang, Wei
Zeng, Zhi
Xu, Wei
Wu, Wenming
Liang, Wenfeng
Zhou, Jia
author_facet Wang, Wei
Zeng, Zhi
Xu, Wei
Wu, Wenming
Liang, Wenfeng
Zhou, Jia
author_sort Wang, Wei
collection PubMed
description A strategy for an on-chip pH regulator is demonstrated computationally and experimentally, based on the diffusion characteristics of aqueous ionic solutions. Micro-flows with specific pH values are formed based on the diffusion behaviors of hydrogen and hydroxide ions in laminar flows. The final achieved pH value and its gradient in the channel can be regulated by the amount of ions transported between laminar flows, and the experimental results can be further generalized based on the normalized Nernst-Planck equation. A smartphone was applied as an image capture and analysis instrument to quantify pH values of liquids in a colorimetric detection process, with monotonic response range of ~1–13.
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spelling pubmed-63155732019-01-10 A Diffusion-Based pH Regulator in Laminar Flows with Smartphone-Based Colorimetric Analysis Wang, Wei Zeng, Zhi Xu, Wei Wu, Wenming Liang, Wenfeng Zhou, Jia Micromachines (Basel) Article A strategy for an on-chip pH regulator is demonstrated computationally and experimentally, based on the diffusion characteristics of aqueous ionic solutions. Micro-flows with specific pH values are formed based on the diffusion behaviors of hydrogen and hydroxide ions in laminar flows. The final achieved pH value and its gradient in the channel can be regulated by the amount of ions transported between laminar flows, and the experimental results can be further generalized based on the normalized Nernst-Planck equation. A smartphone was applied as an image capture and analysis instrument to quantify pH values of liquids in a colorimetric detection process, with monotonic response range of ~1–13. MDPI 2018-11-23 /pmc/articles/PMC6315573/ /pubmed/30477093 http://dx.doi.org/10.3390/mi9120616 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wang, Wei
Zeng, Zhi
Xu, Wei
Wu, Wenming
Liang, Wenfeng
Zhou, Jia
A Diffusion-Based pH Regulator in Laminar Flows with Smartphone-Based Colorimetric Analysis
title A Diffusion-Based pH Regulator in Laminar Flows with Smartphone-Based Colorimetric Analysis
title_full A Diffusion-Based pH Regulator in Laminar Flows with Smartphone-Based Colorimetric Analysis
title_fullStr A Diffusion-Based pH Regulator in Laminar Flows with Smartphone-Based Colorimetric Analysis
title_full_unstemmed A Diffusion-Based pH Regulator in Laminar Flows with Smartphone-Based Colorimetric Analysis
title_short A Diffusion-Based pH Regulator in Laminar Flows with Smartphone-Based Colorimetric Analysis
title_sort diffusion-based ph regulator in laminar flows with smartphone-based colorimetric analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315573/
https://www.ncbi.nlm.nih.gov/pubmed/30477093
http://dx.doi.org/10.3390/mi9120616
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