Pyrrole-Mediated Peptide Cyclization Identified through Genetically Reprogrammed Peptide Synthesis

Flexible in vitro translation (FIT) was used as a screening method to uncover a new methodology for peptide constraining based on the attack of a nucleophilic side-chain functionality onto an oxidized furylalanine side chain. A set of template peptides, each containing furylalanine as furan-modified...

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Detalles Bibliográficos
Autores principales: Decoene, Klaas W., Vannecke, Willem, Passioura, Toby, Suga, Hiroaki, Madder, Annemieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315747/
https://www.ncbi.nlm.nih.gov/pubmed/30380792
http://dx.doi.org/10.3390/biomedicines6040099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315747/
https://www.ncbi.nlm.nih.gov/pubmed/30380792
http://dx.doi.org/10.3390/biomedicines6040099

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