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Pyrrole-Mediated Peptide Cyclization Identified through Genetically Reprogrammed Peptide Synthesis

Flexible in vitro translation (FIT) was used as a screening method to uncover a new methodology for peptide constraining based on the attack of a nucleophilic side-chain functionality onto an oxidized furylalanine side chain. A set of template peptides, each containing furylalanine as furan-modified...

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Detalles Bibliográficos
Autores principales:	Decoene, Klaas W., Vannecke, Willem, Passioura, Toby, Suga, Hiroaki, Madder, Annemieke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315747/ https://www.ncbi.nlm.nih.gov/pubmed/30380792 http://dx.doi.org/10.3390/biomedicines6040099

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