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Role of the Mre11 Complex in Preserving Genome Integrity

DNA double-strand breaks (DSBs) are hazardous lesions that threaten genome integrity and cell survival. The DNA damage response (DDR) safeguards the genome by sensing DSBs, halting cell cycle progression and promoting repair through either non-homologous end joining (NHEJ) or homologous recombinatio...

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Detalles Bibliográficos
Autores principales:	Oh, Julyun, Symington, Lorraine S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315862/ https://www.ncbi.nlm.nih.gov/pubmed/30501098 http://dx.doi.org/10.3390/genes9120589

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