Dual Specificity Phosphatase 6 Protects Neural Stem Cells from β-Amyloid-Induced Cytotoxicity through ERK1/2 Inactivation

Alzheimer’s disease (AD) is a devastating neurodegenerative disease with limited treatment options and no cure. Beta-amyloid (Aβ) is a hallmark of AD that has potent neurotoxicity in neural stem cells (NSCs). Dual specificity phosphatase 6 (DUSP6) is a member of the mitogen-activated protein kinases...

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Detalles Bibliográficos
Autores principales: Liao, Wang, Zheng, Yuqiu, Fang, Wenli, Liao, Shaowei, Xiong, Ying, Li, Yi, Xiao, Songhua, Zhang, Xingcai, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315916/
https://www.ncbi.nlm.nih.gov/pubmed/30572643
http://dx.doi.org/10.3390/biom8040181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315916/
https://www.ncbi.nlm.nih.gov/pubmed/30572643
http://dx.doi.org/10.3390/biom8040181

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