Cargando…

Semantic Multi-Classifier Systems Identify Predictive Processes in Heart Failure Models across Species

Genetic model organisms have the potential of removing blind spots from the underlying gene regulatory networks of human diseases. Allowing analyses under experimental conditions they complement the insights gained from observational data. An inevitable requirement for a successful trans-species tra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lausser, Ludwig, Siegle, Lea, Rottbauer, Wolfgang, Frank, Derk, Just, Steffen, Kestler, Hans A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315933/ https://www.ncbi.nlm.nih.gov/pubmed/30486323 http://dx.doi.org/10.3390/biom8040158

Ejemplares similares

Constraining classifiers in molecular analysis: invariance and robustness
por: Lausser, Ludwig, et al.
Publicado: (2020)

Loss of the novel Vcp (valosin containing protein) interactor Washc4 interferes with autophagy-mediated proteostasis in striated muscle and leads to myopathy in vivo
por: Kustermann, Monika, et al.
Publicado: (2018)

A Boolean network of the crosstalk between IGF and Wnt signaling in aging satellite cells
por: Siegle, Lea, et al.
Publicado: (2018)

Efficient cross-validation traversals in feature subset selection
por: Lausser, Ludwig, et al.
Publicado: (2022)

Atrogin-1 Deficiency Leads to Myopathy and Heart Failure in Zebrafish
por: Bühler, Anja, et al.
Publicado: (2016)

Genetic compensation prevents myopathy and heart failure in an in vivo model of Bag3 deficiency
por: Diofano, Federica, et al.
Publicado: (2020)

Ion Flux Dependent and Independent Functions of Ion Channels in the Vertebrate Heart: Lessons Learned from Zebrafish
por: Keßler, Mirjam, et al.
Publicado: (2012)

Assessing phenotype order in molecular data
por: Lausser, Ludwig, et al.
Publicado: (2019)

Unsupervised domain adaptation for the detection of cardiomegaly in cross-domain chest X-ray images
por: Thiam, Patrick, et al.
Publicado: (2023)

Capturing dynamic relevance in Boolean networks using graph theoretical measures
por: Weidner, Felix M, et al.
Publicado: (2021)

Response to the letter to the editor: On the feasibility of dynamical analysis of network models of biochemical regulation
por: Weidner, Felix M, et al.
Publicado: (2022)

Therapeutic Chemical Screen Identifies Phosphatase Inhibitors to Reconstitute PKB Phosphorylation and Cardiac Contractility in ILK-Deficient Zebrafish
por: Pott, Alexander, et al.
Publicado: (2018)

Classifying patents based on their semantic content
por: Bergeaud, Antonin, et al.
Publicado: (2017)

3D Network exploration and visualisation for lifespan data
por: Hühne, Rolf, et al.
Publicado: (2018)

Stability of Signaling Pathways during Aging—A Boolean Network Approach
por: Schwab, Julian Daniel, et al.
Publicado: (2017)

Loss of dihydrolipoyl succinyltransferase (DLST) leads to reduced resting heart rate in the zebrafish
por: Keßler, Mirjam, et al.
Publicado: (2015)

A systems biology approach to define mechanisms, phenotypes, and drivers in PanNETs with a personalized perspective
por: Werle, Silke D., et al.
Publicado: (2023)

Comparative gene-expression profiling of the large cell variant of gastrointestinal marginal-zone B-cell lymphoma
por: Barth, Thomas F. E., et al.
Publicado: (2017)

Genetics of Cardiovascular Disease: Fishing for Causality
por: Paone, Christoph, et al.
Publicado: (2018)

CRISPR/Cas9-Mediated Constitutive Loss of VCP (Valosin-Containing Protein) Impairs Proteostasis and Leads to Defective Striated Muscle Structure and Function In Vivo
por: Voisard, Philipp, et al.
Publicado: (2022)

Weighted average ensemble-based semantic segmentation in biological electron microscopy images
por: Shaga Devan, Kavitha, et al.
Publicado: (2022)

Tbx20 Is an Essential Regulator of Embryonic Heart Growth in Zebrafish
por: Just, Steffen, et al.
Publicado: (2016)

Long-Chain Acyl-Carnitines Interfere with Mitochondrial ATP Production Leading to Cardiac Dysfunction in Zebrafish
por: Park, Deung-Dae, et al.
Publicado: (2021)

Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart
por: Hirth, Sofia, et al.
Publicado: (2016)

A compact unc45b‐promoter drives muscle‐specific expression in zebrafish and mouse
por: Rudeck, Steven, et al.
Publicado: (2016)

Can Multi-Label Classifiers Help Identify Subjectivity? A Deep Learning Approach to Classifying Cognitive Presence in MOOCs
por: Hu, Yuanyuan, et al.
Publicado: (2022)

Reduced cGMP levels in CSF of AD patients correlate with severity of dementia and current depression
por: Hesse, Raphael, et al.
Publicado: (2017)

Learning to classify species with barcodes
por: Bertolazzi, Paola, et al.
Publicado: (2009)

Darwin’s perception of nature and the question of disenchantment: a semantic analysis across the six editions of On the Origin of Species
por: Jiménez-Pazos, Bárbara
Publicado: (2021)

Multi-class BCGA-ELM based classifier that identifies biomarkers associated with hallmarks of cancer
por: Sachnev, Vasily, et al.
Publicado: (2015)

Artificial Intelligence Learning Semantics via External Resources for Classifying Diagnosis Codes in Discharge Notes
por: Lin, Chin, et al.
Publicado: (2017)

A highly efficient multi-core algorithm for clustering extremely large datasets
por: Kraus, Johann M, et al.
Publicado: (2010)

Enabling semantic queries across federated bioinformatics databases
por: Sima, Ana Claudia, et al.
Publicado: (2019)

Correction to: Darwin’s perception of nature and the question of disenchantment: a semantic analysis across the six editions of On the Origin of Species
por: Jiménez-Pazos, Bárbara
Publicado: (2021)

Semantic-Enhanced Multi-Dimensional Markov Chains on Semantic Trajectories for Predicting Future Locations †
por: Karatzoglou, Antonios, et al.
Publicado: (2018)

Identification of Multi-Functional Enzyme with Multi-Label Classifier
por: Che, Yuxin, et al.
Publicado: (2016)

Identifying and classifying biomedical perturbations in text
por: Rodriguez-Esteban, Raul, et al.
Publicado: (2009)

Identifying and classifying goals for scientific knowledge
por: Boguslav, Mayla R, et al.
Publicado: (2021)

Use of Multi-Date and Multi-Spectral UAS Imagery to Classify Dominant Tree Species in the Wet Miombo Woodlands of Zambia
por: Shamaoma, Hastings, et al.
Publicado: (2023)

NADH Fluorescence Lifetime Imaging Microscopy Reveals Selective Mitochondrial Dysfunction in Neurons Overexpressing Alzheimer’s Disease–Related Proteins
por: Niederschweiberer, Moritz A., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_t71urabo1nt5rr2mn9iehuvvgm