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Engineering of an Anti-Inflammatory Peptide Based on the Disulfide-Rich Linaclotide Scaffold
Inflammatory bowel diseases are a set of complex and debilitating diseases, for which there is no satisfactory treatment. Peptides as small as three amino acids have been shown to have anti-inflammatory activity in mouse models of colitis, but they are likely to be unstable, limiting their developme...
Autores principales: | Cobos, Claudia, Bansal, Paramjit S., Jones, Linda, Wangchuk, Phurpa, Wilson, David, Loukas, Alex, Daly, Norelle L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316043/ https://www.ncbi.nlm.nih.gov/pubmed/30301200 http://dx.doi.org/10.3390/biomedicines6040097 |
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