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Optimization and Validation of a Chromatographic Method for the Quantification of Isoniazid in Urine of Tuberculosis Patients According to the European Medicines Agency Guideline

Isoniazid is a drug that is widely used against tuberculosis. However, it shows high interpatient variability in metabolism kinetics and clinical effect, which complicates the prescription of the medication and jeopardizes the success of the therapy. Therefore, in a specific patient, the pharmacokin...

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Detalles Bibliográficos
Autores principales:	Mishra, Pooja, Albiol-Chiva, Jaume, Bose, Devasish, Durgbanshi, Abhilasha, Peris-Vicente, Juan, Carda-Broch, Samuel, Esteve-Romero, Josep
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316101/ https://www.ncbi.nlm.nih.gov/pubmed/30545003 http://dx.doi.org/10.3390/antibiotics7040107

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