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HSP70 Inhibitor Suppresses IGF-I-Stimulated Migration of Osteoblasts through p44/p42 MAP Kinase

Heat shock protein 70 (HSP70) is a ubiquitously expressed molecular chaperone in a variety of cells including osteoblasts. We previously showed that insulin-like growth factor-I (IGF-I) elicits migration of osteoblast-like MC3T3-E1 cells through the activation of phosphatidylinositol 3-kinase/Akt an...

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Detalles Bibliográficos
Autores principales:	Kawabata, Tetsu, Tokuda, Haruhiko, Sakai, Go, Fujita, Kazuhiko, Matsushima-Nishiwaki, Rie, Kuroyanagi, Gen, Otsuka, Takanobu, Kozawa, Osamu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316248/ https://www.ncbi.nlm.nih.gov/pubmed/30469446 http://dx.doi.org/10.3390/biomedicines6040109

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