Cargando…

Pathological and Molecular Characteristics of Colorectal Cancer with Brain Metastases

Background: Colorectal cancers (CRC) with brain metastases (BM) are scarcely described. The main objective of this study was to determine the molecular profile of CRC with BM. Methods: We included 82 CRC patients with BM. KRAS, NRAS, BRAF and mismatch repair (MMR) status were investigated on primary...

Descripción completa

Detalles Bibliográficos
Autores principales:	Roussille, Pauline, Tachon, Gaelle, Villalva, Claire, Milin, Serge, Frouin, Eric, Godet, Julie, Berger, Antoine, Emambux, Sheik, Petropoulos, Christos, Wager, Michel, Karayan-Tapon, Lucie, Tougeron, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316286/ https://www.ncbi.nlm.nih.gov/pubmed/30544743 http://dx.doi.org/10.3390/cancers10120504

Ejemplares similares

New Artificial Intelligence Score and Immune Infiltrates as Prognostic Factors in Colorectal Cancer With Brain Metastases
por: Randrian, Violaine, et al.
Publicado: (2021)

Detection of Colorectal Cancer and Advanced Adenoma by Liquid Biopsy (Decalib Study): The ddPCR Challenge
por: Junca, Audelaure, et al.
Publicado: (2020)

Impact of STAT3 phosphorylation in glioblastoma stem cells radiosensitization and patient outcome
por: Masliantsev, Konstantin, et al.
Publicado: (2017)

Dual MGMT inactivation by promoter hypermethylation and loss of the long arm of chromosome 10 in glioblastoma
por: Richard, Sophie, et al.
Publicado: (2020)

Crizotinib targets in glioblastoma stem cells
por: Junca, Audelaure, et al.
Publicado: (2017)

Microsatellite Instability: Diagnosis, Heterogeneity, Discordance, and Clinical Impact in Colorectal Cancer
por: Evrard, Camille, et al.
Publicado: (2019)

Deciphering Brain Metastasis Stem Cell Properties From Colorectal Cancer Highlights Specific Stemness Signature and Shared Molecular Features
por: Desette, Amandine, et al.
Publicado: (2023)

MEOX2 Transcription Factor Is Involved in Survival and Adhesion of Glioma Stem-like Cells
por: Tachon, Gaëlle, et al.
Publicado: (2021)

High Intra- and Inter-Tumoral Heterogeneity of RAS Mutations in Colorectal Cancer
por: Jeantet, Marion, et al.
Publicado: (2016)

Targeted RNA‐sequencing assays: a step forward compared to FISH and IHC techniques?
por: Tachon, Gaëlle, et al.
Publicado: (2019)

HSP110 as a Diagnostic but Not a Prognostic Biomarker in Colorectal Cancer With Microsatellite Instability
por: Tachon, Gaelle, et al.
Publicado: (2022)

Histomolecular characterization of intracranial meningiomas developed in patients exposed to high-dose cyproterone acetate: an antiandrogen treatment
por: Portet, Sylvain, et al.
Publicado: (2019)

Cell Cycle Changes after Glioblastoma Stem Cell Irradiation: The Major Role of RAD51
por: Tachon, Gaelle, et al.
Publicado: (2018)

Functional invadopodia formed in glioblastoma stem cells are important regulators of tumor angiogenesis
por: Petropoulos, Christos, et al.
Publicado: (2018)

EGFR, KRAS, BRAF, and HER-2 molecular status in brain metastases from 77 NSCLC patients
por: Villalva, Claire, et al.
Publicado: (2013)

O6-Methylguanine-Methyltransferase (MGMT) Promoter Methylation Status in Glioma Stem-Like Cells is Correlated to Temozolomide Sensitivity Under Differentiation-Promoting Conditions
por: Villalva, Claire, et al.
Publicado: (2012)

Discordance between immunochemistry of mismatch repair proteins and molecular testing of microsatellite instability in colorectal cancer
por: Guyot D'Asnières De Salins, A., et al.
Publicado: (2021)

Heterogeneity of Mismatch Repair Status and Microsatellite Instability between Primary Tumour and Metastasis and Its Implications for Immunotherapy in Colorectal Cancers
por: Evrard, Camille, et al.
Publicado: (2022)

Analysis of factors influencing molecular testing at diagnostic of colorectal cancer
por: Thiebault, Quentin, et al.
Publicado: (2017)

A mesenchymal glioma stem cell profile is related to clinical outcome
por: Balbous, A, et al.
Publicado: (2014)

Prognostic value of increase in transcript levels of Tp73 ΔEx2-3 isoforms in low-grade glioma patients
por: Wager, M, et al.
Publicado: (2006)

A radiosensitizing effect of RAD51 inhibition in glioblastoma stem-like cells
por: Balbous, Anaïs, et al.
Publicado: (2016)

Skin inflammatory response and efficacy of anti-epidermal growth factor receptor therapy in metastatic colorectal cancer (CUTACETUX)
por: Tougeron, David, et al.
Publicado: (2020)

Hippo Signaling Pathway in Gliomas
por: Masliantsev, Konstantin, et al.
Publicado: (2021)

Prognostic molecular markers with no impact on decision-making: the paradox of gliomas based on a prospective study
por: Wager, M, et al.
Publicado: (2008)

Semaphorin, neuropilin and VEGF expression in glial tumours: SEMA3G, a prognostic marker?
por: Karayan-Tapon, L, et al.
Publicado: (2008)

An ANOCEF genomic and transcriptomic microarray study of the response to radiotherapy or to alkylating first-line chemotherapy in glioblastoma patients
por: Ducray, François, et al.
Publicado: (2010)

Cases of Plica Polonica, in Men and Animals
por: Chamseru, M. Roussille
Publicado: (1809)

Outcome-based determination of optimal pyrosequencing assay for MGMT methylation detection in glioblastoma patients
por: Quillien, Véronique, et al.
Publicado: (2014)

Tri-methylation of H3K79 is decreased in TGF-β1-induced epithelial-to-mesenchymal transition in lung cancer
por: Evanno, Emilie, et al.
Publicado: (2017)

Rectum to Medulla Oblongata: Colorectal Cancer Metastasizing to the Brainstem
por: Lakra, Rachaita, et al.
Publicado: (2023)

SETMAR isoforms in glioblastoma: A matter of protein stability
por: Dussaussois-Montagne, Audrey, et al.
Publicado: (2016)

Pathologies respiratoires infectieuses : des concepts à la pratique !
por: Girault, C., et al.
Publicado: (2017)

Widespread overexpression from the four DNA hypermethylated HOX clusters in aggressive (IDHwt) glioma is associated with H3K27me3 depletion and alternative promoter usage
por: Le Boiteux, Elisa, et al.
Publicado: (2021)

Increasing the Number of Thyroid Lesions Classes in Microarray Analysis Improves the Relevance of Diagnostic Markers
por: Fontaine, Jean-Fred, et al.
Publicado: (2009)

The Long Non-Coding RNA HOXA-AS2 Promotes Proliferation of Glioma Stem Cells and Modulates Their Inflammation Pathway Mainly through Post-Transcriptional Regulation
por: Le Boiteux, Elisa, et al.
Publicado: (2022)

Transcriptional alterations in glioma result primarily from DNA methylation–independent mechanisms
por: Court, Franck, et al.
Publicado: (2019)

Shallow whole genome sequencing approach to detect Homologous Recombination Deficiency in the PAOLA-1/ENGOT-OV25 phase-III trial
por: Callens, Celine, et al.
Publicado: (2023)

DGKI Methylation Status Modulates the Prognostic Value of MGMT in Glioblastoma Patients Treated with Combined Radio-Chemotherapy with Temozolomide
por: Etcheverry, Amandine, et al.
Publicado: (2014)

IL22/IL-22R Pathway Induces Cell Survival in Human Glioblastoma Cells
por: Akil, Hussein, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_2flt0vrmljeu3jh6oddidvqit5